Zopiclone

Buy Zopiclone 7.5mg remains to be one of the most common and effective medication in being a short term treatment. contained drug, which falls into group of non-benzodiazepins. It speeds up the process of falling asleep, reduces the awakenings during night. stabilizes sleeping cycle and maintains proper correlation of phases. – Zopiclone 7.5 mg Online Pharmacy | CHANDAH PHARMA.

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 USES OF ZOPICLONE

it is indicated for the short-term treatment of insomnia where sleep initiation or sleep maintenance are prominent symptoms. Long-term use is not recommended, as tolerance, dependence, and addiction can occur with prolonged use. One low quality study found that zopiclone is ineffective in improving sleep quality or increasing sleep time in shift workers – more research in this area has been recommended. Buy Zopiclone 7.5mg

SPECIFIC POPULATIONS

Elderly

similar to other benzodiazepines and nonbenzodiazepine hypnotic drugs, causes impairments in body balance and standing steadiness in individuals who wake up at night or the next morning. Buy Zopiclone 7.5

The combination with alcohol consumption increases these impairments. Partial, but incomplete tolerance develops to these impairments. Zopiclone increases postural sway and increases the number of falls in older people, as well as cognitive side effects. Falls are a significant cause of death in older people.

An extensive review of the medical literature regarding the management of insomnia and the elderly found that considerable evidence of the effectiveness and lasting benefits of nondrug treatments for insomnia exist.

Liver disease

Patients with liver disease eliminate zopiclone much more slowly than normal patients

and in addition experience exaggerated pharmacological effects of the drug.

Miscellaneous

Patients who suffer from muscle weakness due to myasthenia

gravis or have poor respiratory reserves due to severe chronic bronchitis, emphysema, or other lung disease, or have sleep apnoea.

ADVERSE REACTIONS

Sleeping pills, including zopiclone, have been associated with an increased risk of death.^] The British National Formulary states adverse reactions as follows: “taste disturbance; less commonly nausea, vomiting, dizziness, drowsiness, dry mouth, headache; rarely amnesia, confusion, depression, hallucinations, nightmares; very rarely light headedness, incoordination, paradoxical effects […] and sleep-walking also reported”.

CONTRAINDICATIONS

Zopiclone causes impaired driving skills similar to those of benzodiazepines. Patients who drive motor vehicles should not take . Zopiclone induces impairment of psychomotor function. Driving or operating machinery should be avoided after taking zopiclone as effects can carry over to the next day, including impaired hand eye coordination.

EEG AND SLEEP

Similarly to other sedative hypnotic drugs,  causes a decrease in the core body temperature .It causes similar alterations on EEG readings and sleep architecture as benzodiazepines and causes disturbances in sleep architecture on withdrawal as part of its rebound effect.  reduces both delta waves and the number of high-amplitude delta waves whilst increasing low-amplitude waves.Zopiclone reduces the total amount of time spent in REM sleep as well as delaying its onset.Cognitive behavioral therapy has been found to be superior to zopiclone in the treatment of insomnia and has been found to have lasting effects on sleep quality for at least a year after therapy.

OVERDOSE

Zopiclone is sometimes used as a method of suicide. It has a similar fatality index to that of benzodiazepine drugs, apart from temazepam, which is particularly toxic in overdose.Deaths have occurred from z overdose, alone or in combination with other drugs.Overdose  may present with excessive sedation and depressed respiratory function that may progress to coma and possibly death.  combined with alcohol, opiates, or other central nervous system depressants may be even more likely to lead to fatal overdoses.  overdosage can be treated with the benzodiazepine receptor antagonist flumazenil, which displaces zopiclone from its binding site on the benzodiazepine receptor, thereby rapidly reversing its effects.Serious effects on the heart may also occur from a zopiclone overdose when combined with piperazine.